Tumor- and mitochondria-targeted nanoparticles eradicate drug resistant lung cancer through mitochondrial pathway of apoptosis

Chemotherapeutic drugs frequently encounter multidrug resistance. ATP from mitochondria helps overexpression of drug efflux pumps to induce multidrug resistance, so mitochondrial delivery as a means of “repurposing’’ chemotherapeutic drugs currently used in the clinic appears to be a worthwhile stra...

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Detalles Bibliográficos
Autores principales: Wang, He, Zhang, Fangke, Wen, Huaying, Shi, Wenwen, Huang, Qiudi, Huang, Yugang, Xie, Jiacui, Li, Peiyin, Chen, Jianhai, Qin, Linghao, Zhou, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950814/
https://www.ncbi.nlm.nih.gov/pubmed/31918714
http://dx.doi.org/10.1186/s12951-019-0562-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950814/
https://www.ncbi.nlm.nih.gov/pubmed/31918714
http://dx.doi.org/10.1186/s12951-019-0562-3

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