Stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction

Stem cell-derived sheet engineering has been developed as the next-generation treatment for myocardial infarction (MI) and offers attractive advantages in comparison with direct stem cell transplantation and scaffold tissue engineering. Furthermore, induced pluripotent stem cell-derived cell sheets...

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Autores principales: Guo, Rui, Morimatsu, Masatoshi, Feng, Tian, Lan, Feng, Chang, Dehua, Wan, Feng, Ling, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950817/
https://www.ncbi.nlm.nih.gov/pubmed/31915074
http://dx.doi.org/10.1186/s13287-019-1536-y
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author Guo, Rui
Morimatsu, Masatoshi
Feng, Tian
Lan, Feng
Chang, Dehua
Wan, Feng
Ling, Yunpeng
author_facet Guo, Rui
Morimatsu, Masatoshi
Feng, Tian
Lan, Feng
Chang, Dehua
Wan, Feng
Ling, Yunpeng
author_sort Guo, Rui
collection PubMed
description Stem cell-derived sheet engineering has been developed as the next-generation treatment for myocardial infarction (MI) and offers attractive advantages in comparison with direct stem cell transplantation and scaffold tissue engineering. Furthermore, induced pluripotent stem cell-derived cell sheets have been indicated to possess higher potential for MI therapy than other stem cell-derived sheets because of their capacity to form vascularized networks for fabricating thickened human cardiac tissue and their long-term therapeutic effects after transplantation in MI. To date, stem cell sheet transplantation has exhibited a dramatic role in attenuating cardiac dysfunction and improving clinical manifestations of heart failure in MI. In this review, we retrospectively summarized the current applications and strategy of stem cell-derived cell sheet technology for heart tissue repair in MI.
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spelling pubmed-69508172020-01-09 Stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction Guo, Rui Morimatsu, Masatoshi Feng, Tian Lan, Feng Chang, Dehua Wan, Feng Ling, Yunpeng Stem Cell Res Ther Review Stem cell-derived sheet engineering has been developed as the next-generation treatment for myocardial infarction (MI) and offers attractive advantages in comparison with direct stem cell transplantation and scaffold tissue engineering. Furthermore, induced pluripotent stem cell-derived cell sheets have been indicated to possess higher potential for MI therapy than other stem cell-derived sheets because of their capacity to form vascularized networks for fabricating thickened human cardiac tissue and their long-term therapeutic effects after transplantation in MI. To date, stem cell sheet transplantation has exhibited a dramatic role in attenuating cardiac dysfunction and improving clinical manifestations of heart failure in MI. In this review, we retrospectively summarized the current applications and strategy of stem cell-derived cell sheet technology for heart tissue repair in MI. BioMed Central 2020-01-08 /pmc/articles/PMC6950817/ /pubmed/31915074 http://dx.doi.org/10.1186/s13287-019-1536-y Text en © The Author(s). 2020 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Guo, Rui
Morimatsu, Masatoshi
Feng, Tian
Lan, Feng
Chang, Dehua
Wan, Feng
Ling, Yunpeng
Stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction
title Stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction
title_full Stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction
title_fullStr Stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction
title_full_unstemmed Stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction
title_short Stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction
title_sort stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950817/
https://www.ncbi.nlm.nih.gov/pubmed/31915074
http://dx.doi.org/10.1186/s13287-019-1536-y
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