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CNCC: an analysis tool to determine genome-wide DNA break end structure at single-nucleotide resolution

BACKGROUND: DNA double-stranded breaks (DSBs) are potentially deleterious events in a cell. The end structures (blunt, 3′- and 5′-overhangs) at DSB sites contribute to the fate of their repair and provide critical information concerning the consequences of the damage. Therefore, there has been a rec...

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Detalles Bibliográficos
Autores principales: Szlachta, Karol, Raimer, Heather M., Comeau, Laurey D., Wang, Yuh-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950916/
https://www.ncbi.nlm.nih.gov/pubmed/31914926
http://dx.doi.org/10.1186/s12864-019-6436-0