Systemic activation of NLRP3 inflammasome and plasma α-synuclein levels are correlated with motor severity and progression in Parkinson’s disease

BACKGROUND: Emerging evidence indicates that inflammasome-induced inflammation plays a crucial role in the pathogenesis of Parkinson’s disease (PD). Several proteins including α-synuclein trigger the activation of NLRP3 inflammasome. However, few studies examined whether inflammasomes are activated...

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Detalles Bibliográficos
Autores principales: Fan, Zheng, Pan, Yu-Ting, Zhang, Zhi-Yuan, Yang, Hui, Yu, Shu-Yue, Zheng, Yan, Ma, Jing-Hong, Wang, Xiao-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950934/
https://www.ncbi.nlm.nih.gov/pubmed/31915018
http://dx.doi.org/10.1186/s12974-019-1670-6

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