Cargando…

M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma

BACKGROUND: Long non-coding RNAs (lncRNAs) possess significant regulatory functions in multiple biological and pathological processes, especially in cancer. Dysregulated lncRNAs in hepatocellular carcinoma (HCC) and their therapeutic applications remain unclear. METHODS: Differentially expressed lnc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zuo, Xueliang, Chen, Zhiqiang, Gao, Wen, Zhang, Yao, Wang, Jinguo, Wang, Junfeng, Cao, Ming, Cai, Juan, Wu, Jindao, Wang, Xuehao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951025/ https://www.ncbi.nlm.nih.gov/pubmed/31915027 http://dx.doi.org/10.1186/s13045-019-0839-x

Ejemplares similares

CircRHBDD1 augments metabolic rewiring and restricts immunotherapy efficacy via m(6)A modification in hepatocellular carcinoma
por: Cai, Juan, et al.
Publicado: (2022)

MiR-3662 suppresses hepatocellular carcinoma growth through inhibition of HIF-1α-mediated Warburg effect
por: Chen, Zhiqiang, et al.
Publicado: (2018)

LINC00958 Promotes The Malignancy Of Nasopharyngeal Carcinoma By Sponging microRNA-625 And Thus Upregulating NUAK1
por: Chen, Meijuan, et al.
Publicado: (2019)

Derivation and validation of machine learning models for preoperative estimation of microvascular invasion risk in hepatocellular carcinoma
por: Chen, Zhiqiang, et al.
Publicado: (2023)

LINC00958 Promotes the Malignancy of Nasopharyngeal Carcinoma by Sponging microRNA-625 and Thus Upregulating NUAK1 [Retraction]
Publicado: (2023)

circLARP4 induces cellular senescence through regulating miR‐761/RUNX3/p53/p21 signaling in hepatocellular carcinoma
por: Chen, Zhiqiang, et al.
Publicado: (2019)

STAT1-Induced Upregulation lncRNA LINC00958 Accelerates the Epithelial Ovarian Cancer Tumorigenesis by Regulating Wnt/β-Catenin Signaling
por: Xie, Min, et al.
Publicado: (2021)

Profiling of long non-coding RNAs identifies LINC00958 and LINC01296 as candidate oncogenes in bladder cancer
por: Seitz, Anna Katharina, et al.
Publicado: (2017)

LINC00958 promotes bladder cancer carcinogenesis by targeting miR-490-3p and AURKA
por: Zhen, Hongtao, et al.
Publicado: (2021)

M6A-mediated upregulation of circMDK promotes tumorigenesis and acts as a nanotherapeutic target in hepatocellular carcinoma
por: Du, Ashuai, et al.
Publicado: (2022)

LINC00958 promotes proliferation, migration, invasion, and epithelial-mesenchymal transition of oesophageal squamous cell carcinoma cells
por: Wang, Biqi, et al.
Publicado: (2021)

Downregulation of LINC00958 inhibits proliferation, invasion and migration, and promotes apoptosis of colorectal cancer cells by targeting miR-3619-5p
por: Sun, Ye, et al.
Publicado: (2020)

LINC00958 may be a new prognostic biomarker in various cancers: A meta-analysis and bioinformatics analysis
por: Zhang, Helin, et al.
Publicado: (2022)

LINC00958 and HOXC13-AS as key candidate biomarkers in head and neck squamous cell carcinoma by integrated bioinformatics analysis
por: Xiong, Dan, et al.
Publicado: (2020)

LINC00958 promotes the proliferation of TSCC via miR-211-5p/CENPK axis and activating the JAK/STAT3 signaling pathway
por: Jia, Bo, et al.
Publicado: (2021)

The regulation of long non-coding RNA 00958 (LINC00958) for oral squamous cell carcinoma (OSCC) cells death through absent in melanoma 2 (AIM2) depending on microRNA-4306 and Sirtuin1 (SIRT1) in vitro
por: Jiang, Lei, et al.
Publicado: (2021)

IGF2BP3 enhances the mRNA stability of E2F3 by interacting with LINC00958 to promote endometrial carcinoma progression
por: Wang, Cuicui, et al.
Publicado: (2022)

MYC/MAX-Activated LINC00958 Promotes Lung Adenocarcinoma by Oncogenic Transcriptional Reprogramming Through HOXA1 Activation
por: Zhang, Tao, et al.
Publicado: (2022)

M2 macrophage-secreted exosomes promote metastasis and increase vascular permeability in hepatocellular carcinoma
por: Lu, Yiwei, et al.
Publicado: (2023)

Hypomethylation‐mediated activation of cancer/testis antigen KK‐LC‐1 facilitates hepatocellular carcinoma progression through activating the Notch1/Hes1 signalling
por: Chen, Zhiqiang, et al.
Publicado: (2019)

Long noncoding RNA LINC00958 suppresses apoptosis and radiosensitivity of colorectal cancer through targeting miR-422a
por: Liang, Hong, et al.
Publicado: (2021)

Knockdown of LncRNA LINC00958 Inhibits the Proliferation and Migration of NSCLC Cells by MiR-204-3p/KIF2A Axis
por: Wang, Qing, et al.
Publicado: (2021)

LINC00958-MYC positive feedback loop modulates resistance of head and neck squamous cell carcinoma cells to chemo- and radiotherapy in vitro
por: Huang, Shanshan, et al.
Publicado: (2019)

Long noncoding RNA LINC00958 accelerates the proliferation and matrix degradation of the nucleus pulposus by regulating miR-203/SMAD3
por: Zhao, Kunchi, et al.
Publicado: (2019)

Long Noncoding RNAs Serve as Potential Diagnostic Biomarkers for Colorectal Cancer
por: Cai, Juan, et al.
Publicado: (2019)

LINC00958 Inhibits Autophagy of Bladder Cancer Cells via Sponge Adsorption of miR-625-5p to Promote Tumor Angiogenesis and Oxidative Stress
por: Xiao, Ying, et al.
Publicado: (2022)

m(6)A-induced LINC00958 promotes breast cancer tumorigenesis via the miR-378a-3p/YY1 axis
por: Rong, Dongwen, et al.
Publicado: (2021)

circHECTD1 facilitates glutaminolysis to promote gastric cancer progression by targeting miR-1256 and activating β-catenin/c-Myc signaling
por: Cai, Juan, et al.
Publicado: (2019)

Clinical Value and Underlying Mechanisms of Upregulated LINC00485 in Hepatocellular Carcinoma
por: Zhu, Xinyu, et al.
Publicado: (2021)

The interplay of transcriptional coregulator NUPR1 with SREBP1 promotes hepatocellular carcinoma progression via upregulation of lipogenesis
por: Wang, Yongjia, et al.
Publicado: (2022)

FER Regulated by miR-206 Promotes Hepatocellular Carcinoma Progression via NF-κB Signaling
por: Ding, Wenzhou, et al.
Publicado: (2021)

Mechanisms and Implications of Dual-Acting Methotrexate in Folate-Targeted Nanotherapeutic Delivery
por: Wong, Pamela T., et al.
Publicado: (2015)

Retracted: LINC00958 Inhibits Autophagy of Bladder Cancer Cells via Sponge Adsorption of miR-625-5p to Promote Tumor Angiogenesis and Oxidative Stress
por: Longevity, Oxidative Medicine and Cellular
Publicado: (2023)

Upregulated LINC01667 Expression Is Correlated With Poor Prognosis in Hepatocellular Carcinoma
por: Zhang, Kainan, et al.
Publicado: (2021)

Unplanned reoperation after radical gastrectomy for gastric cancer: causes, risk factors, and long-term prognostic influence
por: Zuo, Xueliang, et al.
Publicado: (2018)

Downregulation of PDK4 Increases Lipogenesis and Associates with Poor Prognosis in Hepatocellular Carcinoma
por: Yang, Chen, et al.
Publicado: (2019)

Advances in personalized nanotherapeutics
por: Kaushik, Ajeet, et al.
Publicado: (2017)

Polymeric nanomaterials for nanotherapeutics
por: Vasile, Cornelia
Publicado: (2018)

Targeted nanotherapeutics in cancer
por: Shiekh, Farooq A
Publicado: (2014)

linc00958/miR-185-5p/RSF-1 modulates cisplatin resistance and angiogenesis through AKT1/GSK3β/VEGFA pathway in cervical cancer
por: Tian, Jing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pei4urtm5mqq45vu9ad5lelipg