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Correlation of multicolor images and conventional color fundus photographs with foveal autofluorescence patterns in diabetic macular edema
PURPOSE: The aim of this study is to assess the ability of multicolour imaging (MCI) to detect foveal cysts in diabetic macular edema (DME) and compare it with conventional color fundus photography (CFP) and foveal autofluorescence (FAF) pattern. METHODS: It was a retrospective review of 112 eyes of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951198/ https://www.ncbi.nlm.nih.gov/pubmed/31856492 http://dx.doi.org/10.4103/ijo.IJO_608_19 |
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author | Saurabh, Kumar Roy, Rupak Goel, Sugandha |
author_facet | Saurabh, Kumar Roy, Rupak Goel, Sugandha |
author_sort | Saurabh, Kumar |
collection | PubMed |
description | PURPOSE: The aim of this study is to assess the ability of multicolour imaging (MCI) to detect foveal cysts in diabetic macular edema (DME) and compare it with conventional color fundus photography (CFP) and foveal autofluorescence (FAF) pattern. METHODS: It was a retrospective review of 112 eyes of 84 DME patients with central foveal thickness ≥250 μ who underwent MCI, CFP and shortwave autofluorescence imaging. MCI was performed with Sepctralis spectral domain optical coherence tomography (SDOCT) (Heidelberg Engineering, Germany). RESULTS: 97 (86.6%) eyes had cystoid increased autofluorescence (cystoid iFAF), 9 (8%) had spot iFAF and 6 (5.35%) had irregular decreased FAF (dFAF). Among eyes with cystoid iFAF, OCT detected DME cysts in 93 (95.6%) eyes, MCI in 75 (77.3%) and CFP in 5 (5.15%) eyes. In all these eyes, the location of cysts on OCT and MCI corresponded with the location of cystoid iFAF, whereas none of the eyes with cyst seen on CFP correlated with the location of cystoid iFAF. CONCLUSION: MCI was superior to CFP in detecting DME cysts at fovea. It also correlated with hyperautofluorescence pattern in these eyes. MCI may have a potential role in diabetic retinopathy screening by segregating eyes with DME which would require treatment. Our findings need to be further validated in a larger and prospective study design. |
format | Online Article Text |
id | pubmed-6951198 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-69511982020-01-16 Correlation of multicolor images and conventional color fundus photographs with foveal autofluorescence patterns in diabetic macular edema Saurabh, Kumar Roy, Rupak Goel, Sugandha Indian J Ophthalmol Original Article PURPOSE: The aim of this study is to assess the ability of multicolour imaging (MCI) to detect foveal cysts in diabetic macular edema (DME) and compare it with conventional color fundus photography (CFP) and foveal autofluorescence (FAF) pattern. METHODS: It was a retrospective review of 112 eyes of 84 DME patients with central foveal thickness ≥250 μ who underwent MCI, CFP and shortwave autofluorescence imaging. MCI was performed with Sepctralis spectral domain optical coherence tomography (SDOCT) (Heidelberg Engineering, Germany). RESULTS: 97 (86.6%) eyes had cystoid increased autofluorescence (cystoid iFAF), 9 (8%) had spot iFAF and 6 (5.35%) had irregular decreased FAF (dFAF). Among eyes with cystoid iFAF, OCT detected DME cysts in 93 (95.6%) eyes, MCI in 75 (77.3%) and CFP in 5 (5.15%) eyes. In all these eyes, the location of cysts on OCT and MCI corresponded with the location of cystoid iFAF, whereas none of the eyes with cyst seen on CFP correlated with the location of cystoid iFAF. CONCLUSION: MCI was superior to CFP in detecting DME cysts at fovea. It also correlated with hyperautofluorescence pattern in these eyes. MCI may have a potential role in diabetic retinopathy screening by segregating eyes with DME which would require treatment. Our findings need to be further validated in a larger and prospective study design. Wolters Kluwer - Medknow 2020-01 2019-12-19 /pmc/articles/PMC6951198/ /pubmed/31856492 http://dx.doi.org/10.4103/ijo.IJO_608_19 Text en Copyright: © 2019 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Saurabh, Kumar Roy, Rupak Goel, Sugandha Correlation of multicolor images and conventional color fundus photographs with foveal autofluorescence patterns in diabetic macular edema |
title | Correlation of multicolor images and conventional color fundus photographs with foveal autofluorescence patterns in diabetic macular edema |
title_full | Correlation of multicolor images and conventional color fundus photographs with foveal autofluorescence patterns in diabetic macular edema |
title_fullStr | Correlation of multicolor images and conventional color fundus photographs with foveal autofluorescence patterns in diabetic macular edema |
title_full_unstemmed | Correlation of multicolor images and conventional color fundus photographs with foveal autofluorescence patterns in diabetic macular edema |
title_short | Correlation of multicolor images and conventional color fundus photographs with foveal autofluorescence patterns in diabetic macular edema |
title_sort | correlation of multicolor images and conventional color fundus photographs with foveal autofluorescence patterns in diabetic macular edema |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951198/ https://www.ncbi.nlm.nih.gov/pubmed/31856492 http://dx.doi.org/10.4103/ijo.IJO_608_19 |
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