Cargando…

Low incidence of pachydrusen in central serous chorioretinopathy in an Indian cohort

PURPOSE: The aim of this study is to report the prevalence, clinical and swept-source optical coherence tomography (SS-OCT) characteristics of pachydrusen in eyes with central serous chorioretinopathy (CSCR) and their fellow eyes. METHODS: A total of 264 eyes of 132 patients with a diagnosis of CSCR...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Sumit Randhir, Chakurkar, Renuka, Goud, Abhilash, Chhablani, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951215/
https://www.ncbi.nlm.nih.gov/pubmed/31856486
http://dx.doi.org/10.4103/ijo.IJO_528_19
_version_ 1783486242175844352
author Singh, Sumit Randhir
Chakurkar, Renuka
Goud, Abhilash
Chhablani, Jay
author_facet Singh, Sumit Randhir
Chakurkar, Renuka
Goud, Abhilash
Chhablani, Jay
author_sort Singh, Sumit Randhir
collection PubMed
description PURPOSE: The aim of this study is to report the prevalence, clinical and swept-source optical coherence tomography (SS-OCT) characteristics of pachydrusen in eyes with central serous chorioretinopathy (CSCR) and their fellow eyes. METHODS: A total of 264 eyes of 132 patients with a diagnosis of CSCR (acute/persistent/recurrent/chronic/inactive) in atleast one eye, were analyzed in this retrospective, cross-sectional study. SS-OCT parameters including choroidal thickness (CT), large choroidal vessel layer thickness (LCVT) at fovea and the site of pachydrusen were recorded. Paired t test and analysis of variance (ANOVA) was used to compare CT in eyes with CSCR (subfoveal and site of pachydrusen) and multiple groups respectively. RESULTS: The mean age of the study patients was 42.9 ± 9.5 years with 119 males (90.15%). Bilateral CSCR was present in 31 patients. Nine eyes (chronic, 4; persistent, 2; and inactive/resolved CSCR, 3) showed presence of pachydrusen with an overall prevalence of 6.82% (9 eyes of 9 patients out of 132 patients). There was no significant difference of subfoveal CT (SFCT) in eyes with CSCR (422.4 ± 107.8 μ) vs fellow eyes (407.0 ± 96.5 μ) and eyes with CSCR associated with pachydrusen (413.7 ± 101.5 μ) vs fellow eyes of CSCR eyes with pachydrusen (431.6 ± 188.8 μ) (P = 0.71). LCVT as a percentage of CT was higher at the site of pachydrusen compared to SFCT (69.8% vs. 50.8%). CONCLUSION: CSCR can be associated with pachydrusen with a lower prevalence rate than previously reported. Whether the thickened large choroidal vessels at site of pachydrusen play any role in formation in pachydrusen needs further evaluation.
format Online
Article
Text
id pubmed-6951215
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-69512152020-01-16 Low incidence of pachydrusen in central serous chorioretinopathy in an Indian cohort Singh, Sumit Randhir Chakurkar, Renuka Goud, Abhilash Chhablani, Jay Indian J Ophthalmol Original Article PURPOSE: The aim of this study is to report the prevalence, clinical and swept-source optical coherence tomography (SS-OCT) characteristics of pachydrusen in eyes with central serous chorioretinopathy (CSCR) and their fellow eyes. METHODS: A total of 264 eyes of 132 patients with a diagnosis of CSCR (acute/persistent/recurrent/chronic/inactive) in atleast one eye, were analyzed in this retrospective, cross-sectional study. SS-OCT parameters including choroidal thickness (CT), large choroidal vessel layer thickness (LCVT) at fovea and the site of pachydrusen were recorded. Paired t test and analysis of variance (ANOVA) was used to compare CT in eyes with CSCR (subfoveal and site of pachydrusen) and multiple groups respectively. RESULTS: The mean age of the study patients was 42.9 ± 9.5 years with 119 males (90.15%). Bilateral CSCR was present in 31 patients. Nine eyes (chronic, 4; persistent, 2; and inactive/resolved CSCR, 3) showed presence of pachydrusen with an overall prevalence of 6.82% (9 eyes of 9 patients out of 132 patients). There was no significant difference of subfoveal CT (SFCT) in eyes with CSCR (422.4 ± 107.8 μ) vs fellow eyes (407.0 ± 96.5 μ) and eyes with CSCR associated with pachydrusen (413.7 ± 101.5 μ) vs fellow eyes of CSCR eyes with pachydrusen (431.6 ± 188.8 μ) (P = 0.71). LCVT as a percentage of CT was higher at the site of pachydrusen compared to SFCT (69.8% vs. 50.8%). CONCLUSION: CSCR can be associated with pachydrusen with a lower prevalence rate than previously reported. Whether the thickened large choroidal vessels at site of pachydrusen play any role in formation in pachydrusen needs further evaluation. Wolters Kluwer - Medknow 2020-01 2019-12-19 /pmc/articles/PMC6951215/ /pubmed/31856486 http://dx.doi.org/10.4103/ijo.IJO_528_19 Text en Copyright: © 2019 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Singh, Sumit Randhir
Chakurkar, Renuka
Goud, Abhilash
Chhablani, Jay
Low incidence of pachydrusen in central serous chorioretinopathy in an Indian cohort
title Low incidence of pachydrusen in central serous chorioretinopathy in an Indian cohort
title_full Low incidence of pachydrusen in central serous chorioretinopathy in an Indian cohort
title_fullStr Low incidence of pachydrusen in central serous chorioretinopathy in an Indian cohort
title_full_unstemmed Low incidence of pachydrusen in central serous chorioretinopathy in an Indian cohort
title_short Low incidence of pachydrusen in central serous chorioretinopathy in an Indian cohort
title_sort low incidence of pachydrusen in central serous chorioretinopathy in an indian cohort
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951215/
https://www.ncbi.nlm.nih.gov/pubmed/31856486
http://dx.doi.org/10.4103/ijo.IJO_528_19
work_keys_str_mv AT singhsumitrandhir lowincidenceofpachydrusenincentralserouschorioretinopathyinanindiancohort
AT chakurkarrenuka lowincidenceofpachydrusenincentralserouschorioretinopathyinanindiancohort
AT goudabhilash lowincidenceofpachydrusenincentralserouschorioretinopathyinanindiancohort
AT chhablanijay lowincidenceofpachydrusenincentralserouschorioretinopathyinanindiancohort