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Cardiovascular Risk in Essential Thrombocythemia and Polycythemia Vera: Thrombotic Risk and Survival

Thromboembolic and bleeding events pose a severe risk for patients with Polycythemia Vera (PV) and Essential Thrombocythemia (ET). Many factors can contribute to promoting the thrombotic event due to the interaction between platelets, leukocytes, and endothelium alterations. Moreover, a significant...

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Detalles Bibliográficos
Autores principales: Accurso, Vincenzo, Santoro, Marco, Mancuso, Salvatrice, Contrino, Angelo Davide, Casimiro, Paolo, Sardo, Mariano, Raso, Simona, Di Piazza, Florinda, Perez, Alessandro, Bono, Marco, Russo, Antonio, Siragusa, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951352/
https://www.ncbi.nlm.nih.gov/pubmed/31934318
http://dx.doi.org/10.4084/MJHID.2020.008
Descripción
Sumario:Thromboembolic and bleeding events pose a severe risk for patients with Polycythemia Vera (PV) and Essential Thrombocythemia (ET). Many factors can contribute to promoting the thrombotic event due to the interaction between platelets, leukocytes, and endothelium alterations. Moreover, a significant role can be played by cardiovascular risk factors (CV.R) such as cigarette smoking habits, hypertension, diabetes, obesity and dyslipidemia. In this study, we evaluated the impact that CV.R plays on thrombotic risk and survival in patients with PV and ET.