Population Pharmacokinetic/Pharmacodynamic Analysis of Intravenous Zanamivir in Healthy Adults and Hospitalized Adult and Pediatric Subjects With Influenza

Zanamivir is a potent and highly selective inhibitor of influenza neuraminidase in which the inhibition of this enzyme prevents the virus from infecting other cells and specifically prevents release of the new virion from the host cell membrane. It is available as an oral powder for inhalation and i...

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Detalles Bibliográficos
Autores principales: Zuo, Peiying, Collins, Jon, Okour, Malek, Barth, Aline, Shortino, Denise, Yates, Phillip, Roberts, Grace, Watson, Helen A., Peppercorn, Amanda, Hossain, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951463/
https://www.ncbi.nlm.nih.gov/pubmed/31664778
http://dx.doi.org/10.1111/cts.12697

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