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Generation of a Tumor-Specific Chemokine Gradient Using Oncolytic Vesicular Stomatitis Virus Encoding CXCL9

Genetically modified vesicular stomatitis virus (VSV) is an attractive agent for cancer treatment due to rapid intratumoral replication and observed clinical responses. Although VSV selectively kills malignant cells and can boost antitumor immunity, limited induction of intratumoral immune infiltrat...

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Detalles Bibliográficos
Autores principales: Eckert, Elizabeth C., Nace, Rebecca A., Tonne, Jason M., Evgin, Laura, Vile, Richard G., Russell, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951834/
https://www.ncbi.nlm.nih.gov/pubmed/31930167
http://dx.doi.org/10.1016/j.omto.2019.12.003

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