MSTN Attenuates Cardiac Hypertrophy through Inhibition of Excessive Cardiac Autophagy by Blocking AMPK /mTOR and miR-128/PPARγ/NF-κB

Cardiac hypertrophy, a response of the heart to increased workload, is a major risk factor for heart failure. Myostatin (MSTN) is an inhibitor of myogenesis, regulating the number and size of skeletal myocytes. In recent years, cardiomyocyte autophagy also has been considered to be involved in contr...

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Detalles Bibliográficos
Autores principales: Qi, Hanping, Ren, Jing, Ba, Lina, Song, Chao, Zhang, Qianhui, Cao, Yonggang, Shi, Pilong, Fu, Bowen, Liu, Yongsheng, Sun, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951838/
https://www.ncbi.nlm.nih.gov/pubmed/31923740
http://dx.doi.org/10.1016/j.omtn.2019.12.003

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