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PD-L1, PD-1, LAG-3, and TIM-3 in Melanoma: Expression in Brain Metastases Compared to Corresponding Extracranial Tumors

Background Metastatic melanoma to the brain carries a particularly poor prognosis that may be associated with an attenuated antitumor response in the presence of central nervous system malignancies. Thus, the development of brain metastases could theoretically accelerate cancer progression both loca...

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Detalles Bibliográficos
Autores principales: Wang, Jaeyun Jane, Burger, Peter, Taube, Janis, Soni, Abha, Chaichana, Kaisorn, Sheu, Mary, Belcaid, Zineb, Jackson, Christopher, Lim, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952042/
https://www.ncbi.nlm.nih.gov/pubmed/31938638
http://dx.doi.org/10.7759/cureus.6352