Cargando…

The Fml1-MHF complex suppresses inter-fork strand annealing in fission yeast

Previously we reported that a process called inter-fork strand annealing (IFSA) causes genomic deletions during the termination of DNA replication when an active replication fork converges on a collapsed fork (Morrow et al., 2017). We also identified the FANCM-related DNA helicase Fml1 as a potentia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wong, Io Nam, Neo, Jacqueline PS, Oehler, Judith, Schafhauser, Sophie, Osman, Fekret, Carr, Stephen B, Whitby, Matthew C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952179/ https://www.ncbi.nlm.nih.gov/pubmed/31855181 http://dx.doi.org/10.7554/eLife.49784

Ejemplares similares

Inter-Fork Strand Annealing causes genomic deletions during the termination of DNA replication
por: Morrow, Carl A, et al.
Publicado: (2017)

The PCNA unloader Elg1 promotes recombination at collapsed replication forks in fission yeast
por: Tamang, Sanjeeta, et al.
Publicado: (2019)

Recombination occurs within minutes of replication blockage by RTS1 producing restarted forks that are prone to collapse
por: Nguyen, Michael O, et al.
Publicado: (2015)

Factors affecting template switch recombination associated with restarted DNA replication
por: Jalan, Manisha, et al.
Publicado: (2019)

The FANCM Ortholog Fml1 Promotes Recombination at Stalled Replication Forks and Limits Crossing Over during DNA Double-Strand Break Repair
por: Sun, Weili, et al.
Publicado: (2008)

MHF1–2/CENP-S-X performs distinct roles in centromere metabolism and genetic recombination
por: Bhattacharjee, Sonali, et al.
Publicado: (2013)

MHF1-2/CENP-S-X performs distinct roles in centromere metabolism and genetic recombination
por: Bhattacharjee, Sonali, et al.
Publicado: (2018)

DDK/Hsk1 phosphorylates and targets fission yeast histone deacetylase Hst4 for degradation to stabilize stalled DNA replication forks
por: Aricthota, Shalini, et al.
Publicado: (2021)

Genome rearrangements and pervasive meiotic drive cause hybrid infertility in fission yeast
por: Zanders, Sarah E, et al.
Publicado: (2014)

Multi-step coordination of telomerase recruitment in fission yeast through two coupled telomere-telomerase interfaces
por: Hu, Xichan, et al.
Publicado: (2016)

Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae
por: Manfrini, Nicola, et al.
Publicado: (2015)

SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint
por: Carvalho, Sílvia, et al.
Publicado: (2014)

A sharp Pif1-dependent threshold separates DNA double-strand breaks from critically short telomeres
por: Strecker, Jonathan, et al.
Publicado: (2017)

Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery
por: Tonzi, Peter, et al.
Publicado: (2018)

Rif1 inhibits replication fork progression and controls DNA copy number in Drosophila
por: Munden, Alexander, et al.
Publicado: (2018)

Human HEL308 Localizes to Damaged Replication Forks and Unwinds Lagging Strand Structures
por: Tafel, Agnieszka A., et al.
Publicado: (2011)

CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold
por: Deegan, Tom D, et al.
Publicado: (2020)

SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis
por: Atkins, Alisa, et al.
Publicado: (2020)

Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation
por: McClure, Allison W, et al.
Publicado: (2021)

Ubiquitination-dependent control of sexual differentiation in fission yeast
por: Simonetti, Fabrizio, et al.
Publicado: (2017)

A local ATR-dependent checkpoint pathway is activated by a site-specific replication fork block in human cells
por: Ahmed-Seghir, Sana, et al.
Publicado: (2023)

Proteins pinpoint double strand breaks
por: Cox, Michael M
Publicado: (2013)

CRISPRi is not strand-specific at all loci and redefines the transcriptional landscape
por: Howe, Françoise S, et al.
Publicado: (2017)

The CDK Pef1 and protein phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes
por: Birot, Adrien, et al.
Publicado: (2020)

Spatial inter-centromeric interactions facilitated the emergence of evolutionary new centromeres
por: Guin, Krishnendu, et al.
Publicado: (2020)

A nuclease- and bisulfite-based strategy captures strand-specific R-loops genome-wide
por: Wulfridge, Phillip, et al.
Publicado: (2021)

Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq
por: Claussin, Clémence, et al.
Publicado: (2017)

DNA-PK promotes DNA end resection at DNA double strand breaks in G(0) cells
por: Fowler, Faith C, et al.
Publicado: (2022)

The RecQ DNA helicase Rqh1 constrains Exonuclease 1-dependent recombination at stalled replication forks
por: Osman, Fekret, et al.
Publicado: (2016)

Cisplatin-induced DNA double-strand breaks promote meiotic chromosome synapsis in PRDM9-controlled mouse hybrid sterility
por: Wang, Liu, et al.
Publicado: (2018)

CtIP forms a tetrameric dumbbell-shaped particle which bridges complex DNA end structures for double-strand break repair
por: Wilkinson, Oliver J, et al.
Publicado: (2019)

FANCM-associated proteins MHF1 and MHF2, but not the other Fanconi anemia factors, limit meiotic crossovers
por: Girard, Chloe, et al.
Publicado: (2014)

The ATPase activity of Fml1 is essential for its roles in homologous recombination and DNA repair
por: Nandi, Saikat, et al.
Publicado: (2012)

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice
por: Zhang, Yuan, et al.
Publicado: (2012)

DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis
por: Taylor, Benjamin JM, et al.
Publicado: (2013)

Bidding the CpG island goodbye
por: Greally, John M
Publicado: (2013)

Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates
por: Long, Hannah K, et al.
Publicado: (2013)

Plants regenerated from tissue culture contain stable epigenome changes in rice
por: Stroud, Hume, et al.
Publicado: (2013)

A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis
por: Olive, Virginie, et al.
Publicado: (2013)

When 19 is greater than 92
por: Zeitels, Lauren R, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_iic2uvvibl9apr1ud70fkcbtju