mSphere of Influence: Synthetic Biology of Natural Product Biosynthesis

Mark Walker studies the biosynthesis and engineering of bacterial natural products with the long-term goal of identifying new antibiotic compounds. In this mSphere of Influence, he reflects on how “Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic...

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Detalles Bibliográficos
Autor principal: Walker, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952210/
https://www.ncbi.nlm.nih.gov/pubmed/31915225
http://dx.doi.org/10.1128/mSphere.00954-19
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author Walker, Mark C.
author_facet Walker, Mark C.
author_sort Walker, Mark C.
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description Mark Walker studies the biosynthesis and engineering of bacterial natural products with the long-term goal of identifying new antibiotic compounds. In this mSphere of Influence, he reflects on how “Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A” by K. Yamanaka, K. A. Reynolds, R. D. Kersten, K. S. Ryan, et al. (Proc Natl Acad Sci USA 111:1957–1962, 2014, https://doi.org/10.1073/pnas.1319584111) impacted his thinking on using synthetic biology approaches to study natural product biosynthesis.
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spelling pubmed-69522102020-01-16 mSphere of Influence: Synthetic Biology of Natural Product Biosynthesis Walker, Mark C. mSphere Commentary Mark Walker studies the biosynthesis and engineering of bacterial natural products with the long-term goal of identifying new antibiotic compounds. In this mSphere of Influence, he reflects on how “Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A” by K. Yamanaka, K. A. Reynolds, R. D. Kersten, K. S. Ryan, et al. (Proc Natl Acad Sci USA 111:1957–1962, 2014, https://doi.org/10.1073/pnas.1319584111) impacted his thinking on using synthetic biology approaches to study natural product biosynthesis. American Society for Microbiology 2020-01-08 /pmc/articles/PMC6952210/ /pubmed/31915225 http://dx.doi.org/10.1128/mSphere.00954-19 Text en Copyright © 2020 Walker. https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Commentary
Walker, Mark C.
mSphere of Influence: Synthetic Biology of Natural Product Biosynthesis
title mSphere of Influence: Synthetic Biology of Natural Product Biosynthesis
title_full mSphere of Influence: Synthetic Biology of Natural Product Biosynthesis
title_fullStr mSphere of Influence: Synthetic Biology of Natural Product Biosynthesis
title_full_unstemmed mSphere of Influence: Synthetic Biology of Natural Product Biosynthesis
title_short mSphere of Influence: Synthetic Biology of Natural Product Biosynthesis
title_sort msphere of influence: synthetic biology of natural product biosynthesis
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952210/
https://www.ncbi.nlm.nih.gov/pubmed/31915225
http://dx.doi.org/10.1128/mSphere.00954-19
work_keys_str_mv AT walkermarkc msphereofinfluencesyntheticbiologyofnaturalproductbiosynthesis

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