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First FHM3 mouse model shows spontaneous cortical spreading depolarizations
Here we show, for the first time, spontaneous cortical spreading depolarization (CSD) events – the electrophysiological correlate of the migraine aura – in animals by using the first generated familial hemiplegic migraine type 3 (FHM3) transgenic mouse model. The mutant mice express L263V‐mutated α1...
Autores principales: | Jansen, Nico A., Dehghani, Anisa, Linssen, Margot M. L., Breukel, Cor, Tolner, Else A., van den Maagdenberg, Arn M. J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952313/ https://www.ncbi.nlm.nih.gov/pubmed/31880072 http://dx.doi.org/10.1002/acn3.50971 |
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