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Evidence for positive allosteric modulation of cognitive-enhancing effects of nicotine in healthy human subjects

RATIONALE: Cognitive benefits of nicotinic acetylcholine receptor (nAChR) agonists are well established but have generally been of small magnitude and uncertain clinical significance. A way of raising the effect size may be to facilitate agonist-induced responses by co-administering a nAChR positive...

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Detalles Bibliográficos
Autores principales: Hahn, Britta, Shrieves, Megan E., Olmstead, Cory K., Yuille, Marie B., Chiappelli, Joshua J., Pereira, Edna F. R., Albuquerque, Edson X., Fawcett, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952331/
https://www.ncbi.nlm.nih.gov/pubmed/31686175
http://dx.doi.org/10.1007/s00213-019-05363-4

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