Cargando…

Early-life blockade of NMDA receptors induces epigenetic abnormalities in the adult medial prefrontal cortex: possible involvement in memory impairment in trace fear conditioning

RATIONALE: Several findings indicate that early-life dysfunction of N-methyl-d-aspartate (NMDA) receptors might cause schizophrenia-like abnormalities in adulthood that might be induced by impairments in epigenetic regulation. OBJECTIVES: In the present study, we investigated whether postnatal block...

Descripción completa

Detalles Bibliográficos
Autores principales: Latusz, Joachim, Maćkowiak, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952333/
https://www.ncbi.nlm.nih.gov/pubmed/31654083
http://dx.doi.org/10.1007/s00213-019-05362-5