Excessive cholecalciferol supplementation increases kidney dysfunction associated with intrarenal artery calcification in obese insulin-resistant mice

Diabetes mellitus accelerates vascular calcification (VC) and increases the risk of end-stage renal disease (ESRD). Nevertheless, the impact of VC in renal disease progression in type 2 diabetes mellitus (T2DM) is poorly understood. We addressed the effect of VC and mechanisms involved in renal dysf...

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Detalles Bibliográficos
Autores principales: Almeida, Youri E., Fessel, Melissa R., do Carmo, Luciana Simão, Jorgetti, Vanda, Farias-Silva, Elisângela, Pescatore, Luciana Alves, Gamarra, Lionel F., Andrade, Maria Claudina, Simplicio-Filho, Antonio, Mangueira, Cristóvão Luis Pitangueiras, Rangel, Érika B., Liberman, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952360/
https://www.ncbi.nlm.nih.gov/pubmed/31919470
http://dx.doi.org/10.1038/s41598-019-55501-3

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