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A combined computational and experimental strategy identifies mutations conferring resistance to drugs targeting the BCR-ABL fusion protein
Drug resistance is of increasing concern, especially during the treatments of infectious diseases and cancer. To accelerate the drug discovery process in combating issues of drug resistance, here we developed a computational and experimental strategy to predict drug resistance mutations. Using BCR-A...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952392/ https://www.ncbi.nlm.nih.gov/pubmed/31925328 http://dx.doi.org/10.1038/s42003-019-0743-5 |