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Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin
Antimicrobial resistance is a major global threat that calls for new antibiotics. Globomycin and myxovirescin are two natural antibiotics that target the lipoprotein-processing enzyme, LspA, thereby compromising the integrity of the bacterial cell envelope. As part of a project aimed at understandin...
Autores principales: | Olatunji, Samir, Yu, Xiaoxiao, Bailey, Jonathan, Huang, Chia-Ying, Zapotoczna, Marta, Bowen, Katherine, Remškar, Maja, Müller, Rolf, Scanlan, Eoin M., Geoghegan, Joan A., Olieric, Vincent, Caffrey, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952399/ https://www.ncbi.nlm.nih.gov/pubmed/31919415 http://dx.doi.org/10.1038/s41467-019-13724-y |
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