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Hyperglycemia compromises Rat Cortical Bone by Increasing Osteocyte Lacunar Density and Decreasing Vascular Canal Volume

Uncontrolled diabetes is associated with increased risk of bony fractures. However, the mechanisms have yet to be understood. Using high-resolution synchrotron micro-CT, we calculated the changes in the microstructure of femoral cortices of streptozotocin-induced hyperglycemic (STZ) Wistar Albino ra...

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Detalles Bibliográficos
Autores principales: Ay, Birol, Parolia, Kushagra, Liddell, Robert S., Qiu, Yusheng, Grasselli, Giovanni, Cooper, David M. L., Davies, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952406/
https://www.ncbi.nlm.nih.gov/pubmed/31925331
http://dx.doi.org/10.1038/s42003-019-0747-1