Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS

Nano-flow liquid chromatography tandem mass spectrometry (nano-flow LC–MS/MS) is the mainstay in proteome research because of its excellent sensitivity but often comes at the expense of robustness. Here we show that micro-flow LC–MS/MS using a 1 × 150 mm column shows excellent reproducibility of chr...

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Detalles Bibliográficos
Autores principales: Bian, Yangyang, Zheng, Runsheng, Bayer, Florian P., Wong, Cassandra, Chang, Yun-Chien, Meng, Chen, Zolg, Daniel P., Reinecke, Maria, Zecha, Jana, Wiechmann, Svenja, Heinzlmeir, Stephanie, Scherr, Johannes, Hemmer, Bernhard, Baynham, Mike, Gingras, Anne-Claude, Boychenko, Oleksandr, Kuster, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952431/
https://www.ncbi.nlm.nih.gov/pubmed/31919466
http://dx.doi.org/10.1038/s41467-019-13973-x

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