Synchronous NET and colorectal cancer development: a case report

BACKGROUND: The incidence of synchronous gastrointestinal neuroendocrine tumors (GI-NETs) and colorectal cancer is very low. CASE PRESENTATION: We present a 72-year-old man diagnosed with a rectal neuroendocrine tumor (NET) with multiple organ metastases and simultaneous sigmoid colon cancer. Althou...

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Detalles Bibliográficos
Autores principales: Yumoto, Shinsei, Miyamoto, Yuji, Akiyama, Takahiko, Kiyozumi, Yuki, Eto, Kojiro, Hiyoshi, Yukiharu, Nagai, Yohei, Iwatsuki, Masaaki, Baba, Yoshifumi, Iwagami, Shiro, Yoshida, Naoya, Baba, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952479/
https://www.ncbi.nlm.nih.gov/pubmed/31919616
http://dx.doi.org/10.1186/s40792-020-0777-4
Descripción
Sumario:BACKGROUND: The incidence of synchronous gastrointestinal neuroendocrine tumors (GI-NETs) and colorectal cancer is very low. CASE PRESENTATION: We present a 72-year-old man diagnosed with a rectal neuroendocrine tumor (NET) with multiple organ metastases and simultaneous sigmoid colon cancer. Although the NET was his prognostic factor, he underwent a laparoscopic sigmoidectomy at first because it was expected that the colon cancer would cause obstruction or bleeding during NET treatment. Subsequently, he started taking everolimus. CONCLUSIONS: We should consider surgical resection of the synchronous cancer before systemic therapy for a GI-NET regardless of the difference in prognosis between synchronous tumors, if the cancer may impair the continuation of systemic therapy.

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