Epigenetics: the missing link between genes and psychiatric disorders?


Most studies describing epigenetic modifications have focused on DNA methylation, but fewer studies have focused on histone modifications and noncoding RNAs. Chromatin architecture and CCCTC-binding factor represent important noncoding regulatory elements that warrant further investigation in order...

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Detalles Bibliográficos
Autor principal: Thibaut, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Les Laboratoires Servier 2019
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952746/
https://www.ncbi.nlm.nih.gov/pubmed/31949401
http://dx.doi.org/10.31887/DCNS.2019.21.4/fthibaut
Descripción
Sumario:Most studies describing epigenetic modifications have focused on DNA methylation, but fewer studies have focused on histone modifications and noncoding RNAs. Chromatin architecture and CCCTC-binding factor represent important noncoding regulatory elements that warrant further investigation in order to improve our understanding of the genomic basis of complex diseases such as psychiatric disorders.


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