Cargando…
Identification and Validation Model for Informative Liquid Biopsy-Based microRNA Biomarkers: Insights from Germ Cell Tumor In Vitro, In Vivo and Patient-Derived Data
Liquid biopsy-based biomarkers, such as microRNAs, represent valuable tools for patient management, but often do not make it to integration in the clinic. We aim to explore issues impeding this transition, in the setting of germ cell tumors, for which novel biomarkers are needed. We describe a model...
Autores principales: | Lobo, João, Gillis, Ad J.M., van den Berg, Annette, Dorssers, Lambert C. J., Belge, Gafanzer, Dieckmann, Klaus-Peter, Roest, Henk P., van der Laan, Luc J. W., Gietema, Jourik, Hamilton, Robert J., Jerónimo, Carmen, Henrique, Rui, Salvatori, Daniela, Looijenga, Leendert H. J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952794/ https://www.ncbi.nlm.nih.gov/pubmed/31847394 http://dx.doi.org/10.3390/cells8121637 |
Ejemplares similares
-
Prediction of relapse in stage I testicular germ cell tumor patients on surveillance: investigation of biomarkers
por: Lobo, João, et al.
Publicado: (2020) -
Human Germ Cell Tumors are Developmental Cancers: Impact of Epigenetics on Pathobiology and Clinic
por: Lobo, João, et al.
Publicado: (2019) -
Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell Tumors
por: Rijlaarsdam, Martin A., et al.
Publicado: (2015) -
XIST-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality
por: Lobo, João, et al.
Publicado: (2019) -
Molecular heterogeneity and early metastatic clone selection in testicular germ cell cancer development
por: Dorssers, Lambert C. J., et al.
Publicado: (2019)