Cargando…

Vascular PPARβ/δ Promotes Tumor Angiogenesis and Progression

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors, which function as transcription factors. Among them, PPARβ/δ is highly expressed in endothelial cells. Pharmacological activation with PPARβ/δ agonists had been shown to increase their angiogenic properties. PPARβ/δ has been...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wagner, Kay-Dietrich, Du, Siyue, Martin, Luc, Leccia, Nathalie, Michiels, Jean-François, Wagner, Nicole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952835/ https://www.ncbi.nlm.nih.gov/pubmed/31842402 http://dx.doi.org/10.3390/cells8121623

Ejemplares similares

The Emerging Role of PPAR Beta/Delta in Tumor Angiogenesis
por: Du, Siyue, et al.
Publicado: (2020)

PPARs and Angiogenesis—Implications in Pathology
por: Wagner, Nicole, et al.
Publicado: (2020)

PPARβ activation inhibits melanoma cell proliferation involving repression of the Wilms’ tumour suppressor WT1
por: Michiels, Jean-François, et al.
Publicado: (2010)

Pharmacological Utility of PPAR Modulation for Angiogenesis in Cardiovascular Disease
por: Wagner, Nicole, et al.
Publicado: (2023)

A Role for PPARβ/δ in Ocular Angiogenesis
por: Bishop-Bailey, David
Publicado: (2008)

Altered VEGF Splicing Isoform Balance in Tumor Endothelium Involves Activation of Splicing Factors Srpk1 and Srsf1 by the Wilms’ Tumor Suppressor Wt1
por: Wagner, Kay-Dietrich, et al.
Publicado: (2019)

TRF2 acts as a transcriptional regulator in tumor angiogenesis
por: Maï, Mounir El, et al.
Publicado: (2015)

The Role of PPARs in Disease
por: Wagner, Nicole, et al.
Publicado: (2020)

PPARs and Myocardial Infarction
por: Wagner, Kay-Dietrich, et al.
Publicado: (2020)

Investigating the Role of PPARβ/δ in Retinal Vascular Remodeling Using Pparβ/δ-Deficient Mice
por: Ho, Sze Yuan, et al.
Publicado: (2020)

Context-dependent regulation of endothelial cell metabolism: differential effects of the PPARβ/δ agonist GW0742 and VEGF-A
por: Faulkner, Ashton, et al.
Publicado: (2020)

PPAR Beta/Delta and the Hallmarks of Cancer
por: Wagner, Nicole, et al.
Publicado: (2020)

Recent Insights into the Role of PPARs in Disease
por: Wagner, Nicole, et al.
Publicado: (2023)

PPAR-δ in Vascular Pathophysiology
por: Wang, Nanping
Publicado: (2008)

Unraveling the Role of Peroxisome Proliferator-Activated Receptor β/Δ (PPAR β/Δ) in Angiogenesis Associated with Multiple Myeloma
por: Leone, Patrizia, et al.
Publicado: (2023)

Inducible Conditional Vascular-Specific Overexpression of Peroxisome Proliferator-Activated Receptor Beta/Delta Leads to Rapid Cardiac Hypertrophy
por: Wagner, Kay-Dietrich, et al.
Publicado: (2016)

Erratum to “Inducible Conditional Vascular-Specific Overexpression of Peroxisome Proliferator-Activated Receptor Beta/Delta Leads to Rapid Cardiac Hypertrophy”
por: Wagner, Kay-Dietrich, et al.
Publicado: (2018)

Insights into the Role of PPARβ/δ in NAFLD
por: Chen, Jiapeng, et al.
Publicado: (2018)

PPARβ/δ: Linking Metabolism to Regeneration
por: Magadum, Ajit, et al.
Publicado: (2018)

The Role of PPARβ/δ in Melanoma Metastasis
por: Lim, Jonathan Chee Woei, et al.
Publicado: (2018)

Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging
por: Safwan-Zaiter, Hasan, et al.
Publicado: (2022)

Targeting Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) for Cancer Chemoprevention
por: Peters, Jeffrey M., et al.
Publicado: (2015)

Regulation of Cell Proliferation and Differentiation by PPARβ/δ
por: Müller, Rolf, et al.
Publicado: (2008)

Time (and PPARβ/δ) heals all wounds
por: Short, Ben
Publicado: (2009)

Skin-Targeted Inhibition of PPAR β/δ by Selective Antagonists to Treat PPAR β/δ – Mediated Psoriasis-Like Skin Disease In Vivo
por: Hack, Katrin, et al.
Publicado: (2012)

PPARβ/δ recruits NCOR and regulates transcription reinitiation of ANGPTL4
por: Legrand, Nathalie, et al.
Publicado: (2019)

Small RNA-directed epigenetic programming of embryonic stem cell cardiac differentiation
por: Ghanbarian, Hossein, et al.
Publicado: (2017)

A Role for PPARβ/δ in Tumor Stroma and Tumorigenesis
por: Müller, Rolf, et al.
Publicado: (2008)

PPARβ/δ: Benefits in Coronary Artery Disease and Beyond
por: Leal, Viviane O.
Publicado: (2019)

The PPARβ/δ-AMPK Connection in the Treatment of Insulin Resistance
por: Aguilar-Recarte, David, et al.
Publicado: (2021)

Unraveling the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) expression in colon carcinogenesis
por: Peters, Jeffrey M., et al.
Publicado: (2019)

NO-Donating NSAIDs, PPARδ, and Cancer: Does PPARδ Contribute to Colon Carcinogenesis?
por: Mackenzie, Gerardo G., et al.
Publicado: (2008)

Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment
por: Schumann, Tim, et al.
Publicado: (2015)

Effects of the PPAR-β/δ agonist GW0742 during resuscitated porcine septic shock
por: Wepler, Martin, et al.
Publicado: (2013)

Vaticanol C, a resveratrol tetramer, activates PPARα and PPARβ/δ in vitro and in vivo
por: Tsukamoto, Tomoko, et al.
Publicado: (2010)

PPARα and PPARβ/δ are negatively correlated with proinflammatory markers in leukocytes of an obese pediatric population
por: Vargas-Sánchez, Karina, et al.
Publicado: (2020)

Integrative and systemic approaches for evaluating PPARβ/δ (PPARD) function
por: Giordano Attianese, Greta MP, et al.
Publicado: (2015)

PPARβ/δ: A Key Therapeutic Target in Metabolic Disorders
por: Palomer, Xavier, et al.
Publicado: (2018)

PPARβ/δ-dependent MSC metabolism determines their immunoregulatory properties
por: Contreras-Lopez, R. A., et al.
Publicado: (2020)

The Role of Nrf2 Signaling in PPARβ/δ-Mediated Vascular Protection against Hyperglycemia-Induced Oxidative Stress
por: Jimenez, Rosario, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4jgo5nq397hqs2djc6kif8grq6