Inhibiting alpha subunit of eukaryotic initiation factor 2 dephosphorylation protects injured hepatocytes and reduces hepatocyte proliferation in acute liver injury

AIM: To investigate the impact of alpha subunit of eukaryotic initiation factor 2 (eIF2α) phosphorylation on liver regeneration. METHODS: Male BALB/c mice were intraperitoneally injected with carbon tetrachloride (CCl(4)) to induce liver injury. Human hepatocyte LO2 cells were incubated with thapsig...

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Detalles Bibliográficos
Autores principales: Chen, Guimei, Yang, Xuemei, He, Yihuai, Tang, Yongjing, Tian, Rendong, Huang, Wenge, Chen, Huan, Yang, Fangwan, Li, Ying, Lin, Shide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Medical Schools 2019
Materias:
Reasearch Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952896/
https://www.ncbi.nlm.nih.gov/pubmed/31894919
http://dx.doi.org/10.3325/cmj.2019.60.532

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