pMHC Structural Comparisons as a Pivotal Element to Detect and Validate T-Cell Targets for Vaccine Development and Immunotherapy—A New Methodological Proposal

The search for epitopes that will effectively trigger an immune response remains the “El Dorado” for immunologists. The development of promising immunotherapeutic approaches requires the appropriate targets to elicit a proper immune response. Considering the high degree of HLA/TCR diversity, as well...

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Detalles Bibliográficos
Autores principales: Vianna, Priscila, Mendes, Marcus F.A., Bragatte, Marcelo A., Ferreira, Priscila S., Salzano, Francisco M., Bonamino, Martin H., Vieira, Gustavo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952977/
https://www.ncbi.nlm.nih.gov/pubmed/31766602
http://dx.doi.org/10.3390/cells8121488

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