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Tristetraprolin/ZFP36 Regulates the Turnover of Autoimmune-Associated HLA-DQ mRNAs
HLA class II genes encode highly polymorphic heterodimeric proteins functioning to present antigens to T cells and stimulate a specific immune response. Many HLA genes are strongly associated with autoimmune diseases as they stimulate self-antigen specific CD4(+) T cells driving pathogenic responses...
Autores principales: | Pisapia, Laura, Hamilton, Russell S., Farina, Federica, D’Agostino, Vito, Barba, Pasquale, Strazzullo, Maria, Provenzani, Alessandro, Gianfrani, Carmen, Del Pozzo, Giovanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953012/ https://www.ncbi.nlm.nih.gov/pubmed/31817224 http://dx.doi.org/10.3390/cells8121570 |
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