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The Enigmatic Function of PARP1: From PARylation Activity to PAR Readers

Poly(ADP-ribosyl)ation (PARylation) is catalysed by poly(ADP-ribose) polymerases (PARPs, also known as ARTDs) and then rapidly removed by degrading enzymes. Poly(ADP-ribose) (PAR) is produced from PARylation and provides a delicate and spatiotemporal interaction scaffold for numerous target proteins...

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Detalles Bibliográficos
Autores principales:	Kamaletdinova, Tatiana, Fanaei-Kahrani, Zahra, Wang, Zhao-Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953017/ https://www.ncbi.nlm.nih.gov/pubmed/31842403 http://dx.doi.org/10.3390/cells8121625

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