Cargando…

Upregulation of the Sarco-Endoplasmic Reticulum Calcium ATPase 1 Truncated Isoform Plays a Pathogenic Role in Alzheimer’s Disease

Dysregulation of the Endoplasmic Reticulum (ER) Ca(2+) homeostasis and subsequent ER stress activation occur in Alzheimer Disease (AD). We studied the contribution of the human truncated isoform of the sarco-endoplasmic reticulum Ca(2+) ATPase 1 (S1T) to AD. We examined S1T expression in human AD-af...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bussiere, Renaud, Oulès, Bénédicte, Mary, Arnaud, Vaillant-Beuchot, Loan, Martin, Cécile, El Manaa, Wejdane, Vallée, Déborah, Duplan, Eric, Paterlini-Bréchot, Patrizia, Alves Da Costa, Cristine, Checler, Frédéric, Chami, Mounia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953121/ https://www.ncbi.nlm.nih.gov/pubmed/31795302 http://dx.doi.org/10.3390/cells8121539

Ejemplares similares

Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology
por: El Manaa, Wejdane, et al.
Publicado: (2021)

The Endoplasmic Reticulum Stress/Unfolded Protein Response and Their Contributions to Parkinson’s Disease Physiopathology
por: da Costa, Cristine Alves, et al.
Publicado: (2020)

Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes
por: Del Prete, Dolores, et al.
Publicado: (2016)

The η-secretase-derived APP fragment ηCTF is localized in Golgi, endosomes and extracellular vesicles and contributes to Aβ production
por: Afram, Elissa, et al.
Publicado: (2023)

Molecular Dysfunctions of Mitochondria-Associated Membranes (MAMs) in Alzheimer’s Disease
por: Eysert, Fanny, et al.
Publicado: (2020)

The Evolutionary History of Sarco(endo)plasmic Calcium ATPase (SERCA)
por: Altshuler, Ianina, et al.
Publicado: (2012)

Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation
por: Goiran, Thomas, et al.
Publicado: (2018)

Serca1 Truncated Proteins Unable to Pump Calcium Reduce the Endoplasmic Reticulum Calcium Concentration and Induce Apoptosis
por: Chami, Mounia, et al.
Publicado: (2001)

Leaky Ryanodine receptors increases Amyloid-beta load and induces memory impairments in Tg2576 mouse model of Alzheimer disease
por: Oulès, Bénédicte, et al.
Publicado: (2013)

Ryanodine receptors: Dual contribution to Alzheimer disease?
por: Chami, Mounia, et al.
Publicado: (2014)

Alterations of the Endoplasmic Reticulum (ER) Calcium Signaling Molecular Components in Alzheimer’s Disease
por: Chami, Mounia, et al.
Publicado: (2020)

Drug Interactions With the Ca(2+)-ATPase From Sarco(Endo)Plasmic Reticulum (SERCA)
por: Tadini-Buoninsegni, Francesco, et al.
Publicado: (2018)

Inhibitor of Sarco/Endoplasmic Reticulum Calcium-ATPase Impairs Multiple Steps of Paramyxovirus Replication
por: Kumar, Naveen, et al.
Publicado: (2019)

Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer’s disease models and human brains
por: Vaillant-Beuchot, Loan, et al.
Publicado: (2020)

Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor
por: Bussiere, Renaud, et al.
Publicado: (2017)

Sarco/Endoplasmic Reticulum Ca(2+)-ATPases (SERCA) Contribute to GPCR-Mediated Taste Perception
por: Iguchi, Naoko, et al.
Publicado: (2011)

Inhibition of Sarco-Endoplasmic Reticulum Ca(2+) ATPase Extends the Lifespan in C. elegans Worms
por: García-Casas, Paloma, et al.
Publicado: (2018)

Ryanodine receptors: physiological function and deregulation in Alzheimer disease
por: Del Prete, Dolores, et al.
Publicado: (2014)

The transcription factor XBP-1 in neurodegenerative diseases
por: Checler, Frédéric, et al.
Publicado: (2013)

α-synuclein and p53 functional interplay in physiopathological contexts
por: Alves da Costa, Cristine, et al.
Publicado: (2016)

Sarco(endo)plasmic Reticulum Ca-ATPase-2 Gene: Structure and Transcriptional Regulation of the Human Gene
por: Zarain-Herzberg, Angel, et al.
Publicado: (2002)

Sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) activity is required for V(D)J recombination
por: Chen, Chun-Chin, et al.
Publicado: (2021)

Mitophagy in Alzheimer’s disease: Molecular defects and therapeutic approaches
por: Mary, Arnaud, et al.
Publicado: (2022)

Direct α-synuclein promoter transactivation by the tumor suppressor p53
por: Duplan, Eric, et al.
Publicado: (2016)

The Transcription Factor Function of Parkin: Breaking the Dogma
por: Alves da Costa, Cristine, et al.
Publicado: (2019)

Geographic Structuring of the Plasmodium falciparum Sarco(endo)plasmic Reticulum Ca2+ ATPase (PfSERCA) Gene Diversity
por: Jambou, Ronan, et al.
Publicado: (2010)

Intracellular Alkalinization Induces Cytosolic Ca(2+) Increases by Inhibiting Sarco/Endoplasmic Reticulum Ca(2+)-ATPase (SERCA)
por: Li, Sen, et al.
Publicado: (2012)

Structural Changes of Sarco/Endoplasmic Reticulum Ca(2+)-ATPase Induced by Rutin Arachidonate: A Molecular Dynamics Study
por: Rodríguez, Yoel, et al.
Publicado: (2020)

The SarcoEndoplasmic Reticulum Calcium ATPase (SERCA) pump: a potential target for intervention in aging and skeletal muscle pathologies
por: Xu, Hongyang, et al.
Publicado: (2021)

Sarco/Endoplasmic Reticulum Ca(2+) ATPase 2 Activator Ameliorates Endothelial Dysfunction; Insulin Resistance in Diabetic Mice
por: Kimura, Toyokazu, et al.
Publicado: (2022)

The Effect of Hydrogen Peroxide on Sarco/Endoplasmic and Plasma Membrane Calcium ATPase Gene Expression in Cultured Human Lens Epithelial Cells
por: Marian, M.J, et al.
Publicado: (2008)

Circulating Tumor Cells: Who is the Killer?
por: Paterlini-Bréchot, Patrizia
Publicado: (2014)

Molecularly Distinct Routes of Mitochondrial Ca(2+) Uptake Are Activated Depending on the Activity of the Sarco/Endoplasmic Reticulum Ca(2+) ATPase (SERCA)
por: Waldeck-Weiermair, Markus, et al.
Publicado: (2013)

Effects of acute warming on cardiac and myotomal sarco(endo)plasmic reticulum ATPase (SERCA) of thermally acclimated brown trout (Salmo trutta)
por: Vornanen, Matti
Publicado: (2020)

Role of Reduced Sarco-Endoplasmic Reticulum Ca(2+)-ATPase Function on Sarcoplasmic Reticulum Ca(2+) Alternans in the Intact Rabbit Heart
por: Wang, Lianguo, et al.
Publicado: (2021)

Low-dose lithium supplementation promotes adipose tissue browning and sarco(endo)plasmic reticulum Ca(2+) ATPase uncoupling in muscle
por: Geromella, Mia S., et al.
Publicado: (2022)

Uncoupling Protein 3 (UCP3) Modulates the Activity of Sarco/Endoplasmic Reticulum Ca(2+)-ATPase (SERCA) by Decreasing Mitochondrial ATP Production
por: De Marchi, Umberto, et al.
Publicado: (2011)

Asymmetric dimethylarginine downregulates sarco/endoplasmic reticulum calcium-ATPase 3 and induces endoplasmic reticulum stress in human umbilical vein endothelial cells
por: Guo, Weikang, et al.
Publicado: (2017)

Intermedin protects thapsigargin-induced endoplasmic reticulum stress in cardiomyocytes by modulating protein kinase A and sarco/endoplasmic reticulum Ca(2+)-ATPase
por: Li, Zhidong, et al.
Publicado: (2021)

Circulating Tumor Cells for the Management of Renal Cell Carcinoma
por: Broncy, Lucile, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_jobddtqgsem62v31uki9kfmrh6