Selenium-binding protein 1 transcriptionally activates p21 expression via p53-independent mechanism and its frequent reduction associates with poor prognosis in bladder cancer

BACKGROUND: Recent studies have shown that selenium-binding protein 1 (SELENBP1) is significantly down-regulated in a variety of solid tumors. Nevertheless, the clinical relevance of SELENBP1 in human bladder cancer has not been described in any detail, and the molecular mechanism underlying its inh...

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Detalles Bibliográficos
Autores principales: Wang, Yulei, Zhu, Wenzhen, Chen, Xiaoqing, Wei, Guangnan, Jiang, Guosong, Zhang, Guochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953137/
https://www.ncbi.nlm.nih.gov/pubmed/31918717
http://dx.doi.org/10.1186/s12967-020-02211-4

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