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hUCMSC-extracellular vesicles downregulated hepatic stellate cell activation and reduced liver injury in S. japonicum-infected mice
BACKGROUND: Accumulating evidence shows that mesenchymal stem cells (MSCs) have the potential as a cellular therapy avenue for schistosome-induced liver injury. Extracellular vesicles (EVs) are membranous vesicles released by almost all cell types, and EVs produced by MSCs (MSC-EVs) exert therapeuti...
Autores principales: | Dong, Liyang, Pu, Yanan, Chen, Xiaojun, Qi, Xin, Zhang, Lina, Xu, Lei, Li, Wei, Ma, Yongbin, Zhou, Sha, Zhu, Jifeng, Li, Yalin, Wang, Xuefeng, Su, Chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953150/ https://www.ncbi.nlm.nih.gov/pubmed/31918749 http://dx.doi.org/10.1186/s13287-019-1539-8 |
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