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Madurella mycetomatis infection of the foot: a case report of a neglected tropical disease in a non-endemic region

BACKGROUND: Mycetoma is an uncommon chronic granulomatous infection of cutaneous and subcutaneous tissues that can be caused by filamentous bacteria (actinomycetoma) or fungi (eumycetoma). It is the prerogative of young men between the third and fourth decade and is transmitted through any trauma ca...

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Autores principales: Karrakchou, Basma, Boubnane, Ibtissam, Senouci, Karima, Hassam, Badreddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953183/
https://www.ncbi.nlm.nih.gov/pubmed/31918687
http://dx.doi.org/10.1186/s12895-019-0097-1
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author Karrakchou, Basma
Boubnane, Ibtissam
Senouci, Karima
Hassam, Badreddine
author_facet Karrakchou, Basma
Boubnane, Ibtissam
Senouci, Karima
Hassam, Badreddine
author_sort Karrakchou, Basma
collection PubMed
description BACKGROUND: Mycetoma is an uncommon chronic granulomatous infection of cutaneous and subcutaneous tissues that can be caused by filamentous bacteria (actinomycetoma) or fungi (eumycetoma). It is the prerogative of young men between the third and fourth decade and is transmitted through any trauma causing an inoculating point. The classic clinical triad associates a painless hard and swelling subcutaneous mass, multiple fistulas, and the pathognomonic discharge of grains. Although endemic in many tropical and subtropical countries, mycetoma can also be found in non-endemic areas as in Morocco, and causes then diagnosis problems leading to long lasting complications. Therefore, we should raise awareness of this neglected disease for an earlier management. Under medical treatment however, mycetoma has a slow healing and surgery is often needed, and relapses are possible. CASE PRESENTATION: Herein we report a case of a 64 years old patient, with a history of eumycetoma occurring ten years ago treated with oral terbinafine coupled with surgery. A complete remission was seen after 2 years. He presented a relapse on the previous scar 6 months ago. There wasn’t any bone involvement in the magnetic resonance imaging (MRI). The patient was put under oral terbinafine with a slow but positive outcome. CONCLUSION: Through this case report, we perform a literature review and highlight the importance of increase awareness of mycetoma in clinical practice especially in non-endemic regions.
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spelling pubmed-69531832020-01-14 Madurella mycetomatis infection of the foot: a case report of a neglected tropical disease in a non-endemic region Karrakchou, Basma Boubnane, Ibtissam Senouci, Karima Hassam, Badreddine BMC Dermatol Case Report BACKGROUND: Mycetoma is an uncommon chronic granulomatous infection of cutaneous and subcutaneous tissues that can be caused by filamentous bacteria (actinomycetoma) or fungi (eumycetoma). It is the prerogative of young men between the third and fourth decade and is transmitted through any trauma causing an inoculating point. The classic clinical triad associates a painless hard and swelling subcutaneous mass, multiple fistulas, and the pathognomonic discharge of grains. Although endemic in many tropical and subtropical countries, mycetoma can also be found in non-endemic areas as in Morocco, and causes then diagnosis problems leading to long lasting complications. Therefore, we should raise awareness of this neglected disease for an earlier management. Under medical treatment however, mycetoma has a slow healing and surgery is often needed, and relapses are possible. CASE PRESENTATION: Herein we report a case of a 64 years old patient, with a history of eumycetoma occurring ten years ago treated with oral terbinafine coupled with surgery. A complete remission was seen after 2 years. He presented a relapse on the previous scar 6 months ago. There wasn’t any bone involvement in the magnetic resonance imaging (MRI). The patient was put under oral terbinafine with a slow but positive outcome. CONCLUSION: Through this case report, we perform a literature review and highlight the importance of increase awareness of mycetoma in clinical practice especially in non-endemic regions. BioMed Central 2020-01-10 /pmc/articles/PMC6953183/ /pubmed/31918687 http://dx.doi.org/10.1186/s12895-019-0097-1 Text en © The Author(s). 2020 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Karrakchou, Basma
Boubnane, Ibtissam
Senouci, Karima
Hassam, Badreddine
Madurella mycetomatis infection of the foot: a case report of a neglected tropical disease in a non-endemic region
title Madurella mycetomatis infection of the foot: a case report of a neglected tropical disease in a non-endemic region
title_full Madurella mycetomatis infection of the foot: a case report of a neglected tropical disease in a non-endemic region
title_fullStr Madurella mycetomatis infection of the foot: a case report of a neglected tropical disease in a non-endemic region
title_full_unstemmed Madurella mycetomatis infection of the foot: a case report of a neglected tropical disease in a non-endemic region
title_short Madurella mycetomatis infection of the foot: a case report of a neglected tropical disease in a non-endemic region
title_sort madurella mycetomatis infection of the foot: a case report of a neglected tropical disease in a non-endemic region
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953183/
https://www.ncbi.nlm.nih.gov/pubmed/31918687
http://dx.doi.org/10.1186/s12895-019-0097-1
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