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IGF-1 enhances BMSC viability, migration, and anti-apoptosis in myocardial infarction via secreted frizzled-related protein 2 pathway
BACKGROUND: Bone marrow mesenchymal stem cell (BMSC) transplantation represents a promising therapeutic strategy for ischemic heart disease. However, its effects are hampered by the poor viability of transplanted cells and the hostile microenvironment of the ischemic region. Insulin-like growth fact...
Autores principales: | Lin, Mingzhuo, Liu, Xinyue, Zheng, Haoxiao, Huang, Xiaohui, Wu, Yu, Huang, Anqing, Zhu, Hailan, Hu, Yunzhao, Mai, Weiyi, Huang, Yuli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953226/ https://www.ncbi.nlm.nih.gov/pubmed/31918758 http://dx.doi.org/10.1186/s13287-019-1544-y |
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