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Targeting hypoxia in tumor: a new promising therapeutic strategy

Low oxygen condition (hypoxia) is considered a hallmark of rapidly growing solid tumors. The presence of hypoxia renders tumor cells resistant to conventional chemo- and radio-therapy selecting a more malignant and invasive phenotype, and playing a negative role in patient prognosis. This commentary...

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Detalles Bibliográficos
Autores principales: Bosco, Maria Carla, D’Orazi, Gabriella, Del Bufalo, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953227/
https://www.ncbi.nlm.nih.gov/pubmed/31924239
http://dx.doi.org/10.1186/s13046-019-1517-0