Identification of Antibodies Targeting the H3N2 Hemagglutinin Receptor Binding Site following Vaccination of Humans

Antibodies targeting the receptor binding site (RBS) of the influenza virus hemagglutinin (HA) protein are usually not broadly reactive because their footprints are typically large and extend to nearby variable HA residues. Here, we identify several human H3N2 HA RBS-targeting monoclonal antibodies...

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Detalles Bibliográficos
Autores principales: Zost, Seth J., Lee, Juhye, Gumina, Megan E., Parkhouse, Kaela, Henry, Carole, Wu, Nicholas C., Lee, Chang-Chun D., Wilson, Ian A., Wilson, Patrick C., Bloom, Jesse D., Hensley, Scott E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953393/
https://www.ncbi.nlm.nih.gov/pubmed/31875553
http://dx.doi.org/10.1016/j.celrep.2019.11.084

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