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Salmonella Effector SteE Converts the Mammalian Serine/Threonine Kinase GSK3 into a Tyrosine Kinase to Direct Macrophage Polarization

Many Gram-negative bacterial pathogens antagonize anti-bacterial immunity through translocated effector proteins that inhibit pro-inflammatory signaling. In addition, the intracellular pathogen Salmonella enterica serovar Typhimurium initiates an anti-inflammatory transcriptional response in macroph...

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Detalles Bibliográficos
Autores principales: Panagi, Ioanna, Jennings, Elliott, Zeng, Jingkun, Günster, Regina A., Stones, Cullum D., Mak, Hazel, Jin, Enkai, Stapels, Daphne A.C., Subari, Nur.Z., Pham, Trung H.M., Brewer, Susan M., Ong, Samantha Y.Q., Monack, Denise M., Helaine, Sophie, Thurston, Teresa L.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953433/
https://www.ncbi.nlm.nih.gov/pubmed/31862381
http://dx.doi.org/10.1016/j.chom.2019.11.002