SWI/SNF complex subunit BAF60a represses hepatic ureagenesis through a crosstalk between YB-1 and PGC-1α

OBJECTIVE: Ureagenesis predominantly occurs in the liver and functions to remove ammonia, and the dysregulation of ureagenesis leads to the development of hyperammonemia. Recent studies have shown that ureagenesis is under the control of nutrient signals, but the mechanism remains elusive. Therefore...

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Detalles Bibliográficos
Autores principales: Zhang, Wenxiang, Dong, Zhewen, Xu, Mengyi, Zhang, Shiyao, Liu, Chang, Chen, Siyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953711/
https://www.ncbi.nlm.nih.gov/pubmed/32029232
http://dx.doi.org/10.1016/j.molmet.2019.12.007

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