Cargando…

Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA

Glucocorticoid (GR) and mineralocorticoid receptors (MR) are believed to classically bind DNA as homodimers or MR-GR heterodimers to influence gene regulation in response to pulsatile basal or stress-evoked glucocorticoid secretion. Pulsed corticosterone presentation reveals MR and GR co-occupy DNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pooley, John R., Rivers, Caroline A., Kilcooley, Michael T., Paul, Susana N., Cavga, Ayse Derya, Kershaw, Yvonne M., Muratcioglu, Serena, Gursoy, Attila, Keskin, Ozlem, Lightman, Stafford L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953809/ https://www.ncbi.nlm.nih.gov/pubmed/31923266 http://dx.doi.org/10.1371/journal.pone.0227520

Ejemplares similares

Glucocorticoid Receptor–Tethered Mineralocorticoid Receptors Increase Glucocorticoid-Induced Transcriptional Responses
por: Rivers, Caroline A, et al.
Publicado: (2019)

The Origin of Glucocorticoid Hormone Oscillations
por: Walker, Jamie J., et al.
Publicado: (2012)

Ultradian glucocorticoid exposure directs gene-dependent and tissue-specific mRNA expression patterns in vivo
por: George, Charlotte L., et al.
Publicado: (2017)

Phase-shifting the circadian glucocorticoid profile induces disordered feeding behaviour by dysregulating hypothalamic neuropeptide gene expression
por: Yoshimura, Mitsuhiro, et al.
Publicado: (2023)

Roles of the Glucocorticoid and Mineralocorticoid Receptors in Skin Pathophysiology
por: Sevilla, Lisa M., et al.
Publicado: (2018)

The structural network of Interleukin-10 and its implications in inflammation and cancer
por: Acuner-Ozbabacan, Ece Saliha, et al.
Publicado: (2014)

GLUCOCORTICOID-INDUCED HYPERTENSION AND CARDIAC INJURY: EFFECTS OF MINERALOCORTICOID AND GLUCOCORTICOID RECEPTOR ANTAGONISM
por: HATTORI, TAKUYA, et al.
Publicado: (2013)

Benign adrenal adenomas secreting excess mineralocorticoids and glucocorticoids
por: Yoon, Vivienne, et al.
Publicado: (2013)

Blunted glucocorticoid and mineralocorticoid sensitivity to stress in people with diabetes
por: Carvalho, Livia A., et al.
Publicado: (2015)

Glucocorticoid and Mineralocorticoid Receptors in the Brain: A Transcriptional Perspective
por: Koning, Anne-Sophie C A M, et al.
Publicado: (2019)

One Hormone for Two Receptors: Exploring Glucocorticoid Actions Mediated by the Glucocorticoid and Mineralocorticoid Receptors
por: Petrillo, Maria G, et al.
Publicado: (2021)

Structural analysis of the evolution of steroid specificity in the mineralocorticoid and glucocorticoid receptors
por: Baker, Michael E, et al.
Publicado: (2007)

Role of glucocorticoid negative feedback in the regulation of HPA axis pulsatility
por: Gjerstad, Julia K, et al.
Publicado: (2018)

Dynamic regulation of glucocorticoid signalling in health and disease
por: Biddie, Simon C., et al.
Publicado: (2012)

Glucocorticoid-dependent transcription in skin requires epidermal expression of the glucocorticoid receptor and is modulated by the mineralocorticoid receptor
por: Sevilla, Lisa M., et al.
Publicado: (2020)

Crosstalk between glucocorticoid and mineralocorticoid receptors boosts glucocorticoid-induced killing of multiple myeloma cells
por: Clarisse, Dorien, et al.
Publicado: (2023)

HotPoint: hot spot prediction server for protein interfaces
por: Tuncbag, Nurcan, et al.
Publicado: (2010)

HotRegion: a database of predicted hot spot clusters
por: Cukuroglu, Engin, et al.
Publicado: (2012)

Interaction prediction and classification of PDZ domains
por: Kalyoncu, Sibel, et al.
Publicado: (2010)

Human Cancer Protein-Protein Interaction Network: A Structural Perspective
por: Kar, Gozde, et al.
Publicado: (2009)

Is Persistent Post-COVID Headache Associated With Protein-Protein Interactions Between Antibodies Against Viral Spike Protein and CGRP Receptor?: A Case Report
por: Özkan, Esra, et al.
Publicado: (2022)

A Comparative Molecular Dynamics Study of Methylation State Specificity of JMJD2A
por: Ulucan, Ozlem, et al.
Publicado: (2011)

A novel role for the mineralocorticoid receptor in glucocorticoid driven vascular calcification
por: Zhu, Dongxing, et al.
Publicado: (2016)

The mineralocorticoid receptor knockout in medaka is further validated by glucocorticoid receptor compensation
por: Sakamoto, Tatsuya, et al.
Publicado: (2017)

Glucocorticoid and mineralocorticoid receptor expression in critical illness: A narrative review
por: Vassiliou, Alice G, et al.
Publicado: (2021)

The Glucocorticoid Receptor is Required for Efficient Aldosterone-Induced Transcription by the Mineralocorticoid Receptor.
por: Johnson, Thomas A., et al.
Publicado: (2023)

Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5
por: Hartmann, Jakob, et al.
Publicado: (2021)

The emerging importance of ultradian glucocorticoid rhythms within metabolic pathology
por: Flynn, Benjamin P., et al.
Publicado: (2018)

The HSP90 Molecular Chaperone Cycle Regulates Cyclical Transcriptional Dynamics of the Glucocorticoid Receptor and Its Coregulatory Molecules CBP/p300 During Ultradian Ligand Treatment
por: Conway-Campbell, Becky L., et al.
Publicado: (2011)

Interactome analysis of Bag-1 isoforms reveals novel interaction partners in endoplasmic reticulum-associated degradation
por: Can, Nisan Denizce, et al.
Publicado: (2021)

Prolonged treatment with the synthetic glucocorticoid methylprednisolone affects adrenal steroidogenic function and response to inflammatory stress in the rat
por: Spiga, Francesca, et al.
Publicado: (2020)

Genome-Wide Identification of Basic Helix–Loop–Helix and NF-1 Motifs Underlying GR Binding Sites in Male Rat Hippocampus
por: Pooley, John R., et al.
Publicado: (2017)

Subcutaneous pulsatile glucocorticoid replacement therapy
por: Russell, Georgina M, et al.
Publicado: (2014)

Expression of amygdala mineralocorticoid receptor and glucocorticoid receptor in the single-prolonged stress rats
por: Han, Fang, et al.
Publicado: (2014)

GLUCOCORTICOIDS ACTIVATE CARDIAC MINERALOCORTICOID RECEPTORS IN ADRENALECTOMIZED DAHL SALT-SENSITIVE RATS
por: OHTAKE, MASAFUMI, et al.
Publicado: (2014)

Membrane Associated Synaptic Mineralocorticoid and Glucocorticoid Receptors Are Rapid Regulators of Dendritic Spines
por: Russo, Manuela F., et al.
Publicado: (2016)

SAT-740 Plasma Glucocorticoids and Mineralocorticoids Are Associated to Metabolic Syndrome Features in Women
por: Ostinelli, Giada, et al.
Publicado: (2020)

Loss of central mineralocorticoid or glucocorticoid receptors impacts auditory nerve processing in the cochlea
por: Marchetta, Philine, et al.
Publicado: (2022)

Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver
por: Flynn, Benjamin P., et al.
Publicado: (2021)

HotSprint: database of computational hot spots in protein interfaces
por: Guney, Emre, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_nf1fl2tsqoauq5tgnbt1rdjd0j