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Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA

Glucocorticoid (GR) and mineralocorticoid receptors (MR) are believed to classically bind DNA as homodimers or MR-GR heterodimers to influence gene regulation in response to pulsatile basal or stress-evoked glucocorticoid secretion. Pulsed corticosterone presentation reveals MR and GR co-occupy DNA...

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Detalles Bibliográficos
Autores principales:	Pooley, John R., Rivers, Caroline A., Kilcooley, Michael T., Paul, Susana N., Cavga, Ayse Derya, Kershaw, Yvonne M., Muratcioglu, Serena, Gursoy, Attila, Keskin, Ozlem, Lightman, Stafford L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953809/ https://www.ncbi.nlm.nih.gov/pubmed/31923266 http://dx.doi.org/10.1371/journal.pone.0227520

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