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A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity

The mammarenavirus Lassa (LASV) is highly prevalent in West Africa where it infects several hundred thousand individuals annually resulting in a high number of Lassa fever (LF) cases, a febrile disease associated with high morbidity and significant mortality. Mounting evidence indicates that the wor...

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Detalles Bibliográficos
Autores principales: Cubitt, Beatrice, Ortiz-Riano, Emilio, Cheng, Benson YH., Kim, Yu-Jin, Yeh, Charles D., Chen, Catherine Z., Southall, N.O.E., Zheng, Wei, Martinez-Sobrido, Luis, de la Torre, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954049/
https://www.ncbi.nlm.nih.gov/pubmed/31786250
http://dx.doi.org/10.1016/j.antiviral.2019.104667