Cargando…
A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity
The mammarenavirus Lassa (LASV) is highly prevalent in West Africa where it infects several hundred thousand individuals annually resulting in a high number of Lassa fever (LF) cases, a febrile disease associated with high morbidity and significant mortality. Mounting evidence indicates that the wor...
Autores principales: | Cubitt, Beatrice, Ortiz-Riano, Emilio, Cheng, Benson YH., Kim, Yu-Jin, Yeh, Charles D., Chen, Catherine Z., Southall, N.O.E., Zheng, Wei, Martinez-Sobrido, Luis, de la Torre, Juan C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954049/ https://www.ncbi.nlm.nih.gov/pubmed/31786250 http://dx.doi.org/10.1016/j.antiviral.2019.104667 |
Ejemplares similares
-
Emerging antiviral resistant strains of influenza A and the potential therapeutic targets within the viral ribonucleoprotein (vRNP) complex
por: Davis, Alicia M, et al.
Publicado: (2014) -
Nuclear localized Influenza nucleoprotein N-terminal deletion mutant is deficient in functional vRNP formation
por: Sanchez, Abel, et al.
Publicado: (2014) -
Contemporary medicinal chemistry strategies for the discovery and optimization of influenza inhibitors targeting vRNP constituent proteins
por: Hou, Lingxin, et al.
Publicado: (2022) -
Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import
por: Götz, Veronika, et al.
Publicado: (2016) -
Corrigendum: Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import
por: Götz, Veronika, et al.
Publicado: (2016)