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NMMHC IIA Inhibition Ameliorates Cerebral Ischemic/Reperfusion-Induced Neuronal Apoptosis Through Caspase-3/ROCK1/MLC Pathway

PURPOSE: Our previous studies have indicated that non-muscle myosin heavy chain IIA (NMMHC IIA) is involved in H(2)O(2)-induced neuronal apoptosis, which is associated with the positive feedback loop of caspase-3/ROCK1/MLC pathway. However, the neuroprotective effect of NMMHC IIA inhibition with an...

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Detalles Bibliográficos
Autores principales:	Wang, Guang-Yun, Wang, Tie-Zheng, Zhang, Yuan-Yuan, Li, Fang, Yu, Bo-Yang, Kou, Jun-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954088/ https://www.ncbi.nlm.nih.gov/pubmed/32021088 http://dx.doi.org/10.2147/DDDT.S230882

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