Loss of PARP-1 attenuates diabetic arteriosclerotic calcification via Stat1/Runx2 axis

Accelerated atherosclerotic calcification is responsible for plaque burden, especially in diabetes. The regulatory mechanism for atherosclerotic calcification in diabetes is poorly characterized. Here we show that deletion of PARP-1, a main enzyme in diverse metabolic complications, attenuates diabe...

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Detalles Bibliográficos
Autores principales: Li, Peng, Wang, Ying, Liu, Xue, Liu, Bin, Wang, Zhao-yang, Xie, Fei, Qiao, Wen, Liang, Er-shun, Lu, Qing-hua, Zhang, Ming-xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954221/
https://www.ncbi.nlm.nih.gov/pubmed/31924749
http://dx.doi.org/10.1038/s41419-019-2215-8

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