Dual-initiation promoters with intertwined canonical and TCT/TOP transcription start sites diversify transcript processing

Variations in transcription start site (TSS) selection reflect diversity of preinitiation complexes and can impact on post-transcriptional RNA fates. Most metazoan polymerase II-transcribed genes carry canonical initiation with pyrimidine/purine (YR) dinucleotide, while translation machinery-associa...

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Detalles Bibliográficos
Autores principales: Nepal, Chirag, Hadzhiev, Yavor, Balwierz, Piotr, Tarifeño-Saldivia, Estefanía, Cardenas, Ryan, Wragg, Joseph W., Suzuki, Ana-Maria, Carninci, Piero, Peers, Bernard, Lenhard, Boris, Andersen, Jesper B., Müller, Ferenc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954239/
https://www.ncbi.nlm.nih.gov/pubmed/31924754
http://dx.doi.org/10.1038/s41467-019-13687-0

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