In situ readout of DNA barcodes and single base edits facilitated by in vitro transcription

Molecular barcoding technologies that uniquely identify single cells are hampered by limitations in barcode measurement. Readout by sequencing does not preserve the spatial organization of cells in tissues, whereas imaging methods preserve spatial structure but are less sensitive to barcode sequence...

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Detalles Bibliográficos
Autores principales: Askary, Amjad, Sanchez-Guardado, Luis, Linton, James M., Chadly, Duncan M., Budde, Mark W., Cai, Long, Lois, Carlos, Elowitz, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954335/
https://www.ncbi.nlm.nih.gov/pubmed/31740838
http://dx.doi.org/10.1038/s41587-019-0299-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954335/
https://www.ncbi.nlm.nih.gov/pubmed/31740838
http://dx.doi.org/10.1038/s41587-019-0299-4

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