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In situ readout of DNA barcodes and single base edits facilitated by in vitro transcription
Molecular barcoding technologies that uniquely identify single cells are hampered by limitations in barcode measurement. Readout by sequencing does not preserve the spatial organization of cells in tissues, whereas imaging methods preserve spatial structure but are less sensitive to barcode sequence...
Autores principales: | Askary, Amjad, Sanchez-Guardado, Luis, Linton, James M., Chadly, Duncan M., Budde, Mark W., Cai, Long, Lois, Carlos, Elowitz, Michael B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954335/ https://www.ncbi.nlm.nih.gov/pubmed/31740838 http://dx.doi.org/10.1038/s41587-019-0299-4 |
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