Cargando…
Revealing tumor heterogeneity of breast cancer by utilizing the linkage between somatic and germline mutations
The intra-tumor heterogeneity is associated with cancer progression and therapeutic resistance, such as in breast cancer. While the existing methods for studying tumor heterogeneity only analyze variant allele frequency (VAF), the genotype of variant is also informative for inferring subclones, whic...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954402/ https://www.ncbi.nlm.nih.gov/pubmed/30239581 http://dx.doi.org/10.1093/bib/bby084 |