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DSS1 interacts with and stimulates RAD52 to promote the repair of DSBs

The proper repair of deleterious DNA lesions such as double strand breaks prevents genomic instability and carcinogenesis. In yeast, the Rad52 protein mediates DSB repair via homologous recombination. In mammalian cells, despite the presence of the RAD52 protein, the tumour suppressor protein BRCA2...

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Detalles Bibliográficos
Autores principales:	Stefanovie, Barbora, Hengel, Sarah R, Mlcouskova, Jarmila, Prochazkova, Jana, Spirek, Mario, Nikulenkov, Fedor, Nemecek, Daniel, Koch, Brandon G, Bain, Fletcher E, Yu, Liping, Spies, Maria, Krejci, Lumir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954417/ https://www.ncbi.nlm.nih.gov/pubmed/31799622 http://dx.doi.org/10.1093/nar/gkz1052

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