Point mutations in topoisomerase I alter the mutation spectrum in E. coli and impact the emergence of drug resistance genotypes

Identifying the molecular mechanisms that give rise to genetic variation is essential for the understanding of evolutionary processes. Previously, we have used adaptive laboratory evolution to enable biomass synthesis from CO(2) in Escherichia coli. Genetic analysis of adapted clones from two indepe...

Descripción completa

Detalles Bibliográficos
Autores principales: Bachar, Amit, Itzhaki, Elad, Gleizer, Shmuel, Shamshoom, Melina, Milo, Ron, Antonovsky, Niv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954433/
https://www.ncbi.nlm.nih.gov/pubmed/31777935
http://dx.doi.org/10.1093/nar/gkz1100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954433/
https://www.ncbi.nlm.nih.gov/pubmed/31777935
http://dx.doi.org/10.1093/nar/gkz1100

Ejemplares similares